منابع مشابه
Optimizing biomarkers and endpoints in oral cancer chemoprevention trials.
Chemoprevention, defined as the use of natural, synthetic, or biologic compounds to halt, reverse, or prevent the initial phases of carcinogenesis or the progression of neoplastic cells to cancer, has produced successes, but progress has been slow. Notably, in the field of oral cancer prevention and despite extensive clinical investigations, a standard systemic therapy for patients with oral pr...
متن کاملFinasteride treatment of female pattern hair loss.
OBJECTIVE To evaluate the efficacy of oral finasteride therapy associated with an oral contraceptive containing drospirenone and ethinyl estradiol in premenopausal women with female pattern hair loss. SETTING Outpatient consultation for hair disorders at the Department of Dermatology, University of Bologna. PATIENTS AND INTERVENTION Thirty-seven women with female pattern hair loss were trea...
متن کاملFinasteride and dutasteride may reduce melanoma risk.
Malignant melanoma is an androgen-dependent tumor. Androgen blockade enhances response to the melanoma vaccine. In their study, Zhang et al reported that a history of teenage acne in women may be a novel risk factor for melanoma independent of other risk factors. Acne in women is related to androgens and can be treated with finasteride. Both finasteride and dutasteride prevent the conversion of...
متن کاملCancer Chemoprevention
1Biology Department, College of Science, UAE University, Al-Ain 17551, UAE 2Zoology Department, Faculty of Science, Cairo University, Cairo 12613, Egypt 3Department for Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna Pot 111, Ljubljana, Slovenia 4Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA 5Experimental Tum...
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Prostate cancer management has focused on early detection and treatment, but the prolonged development cycle of prostate cancer suggests that prevention may be a preferable approach. Finasteride and dutasteride, inhibitors of 5 -reductase, inhibit conversion of testosterone to dihydrotestosterone (a potent androgen) and have low toxicity, which makes them attractive chemopreventive agents. Both...
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ژورنال
عنوان ژورنال: Nature Reviews Urology
سال: 2010
ISSN: 1759-4812,1759-4820
DOI: 10.1038/nrurol.2010.33